doi:10.1016/0040-4020(93)80019-P
Copyright © 1993 Published by Elsevier Science Ltd. All
rights reserved.
Alkaloids of the Mexican Bean Beetle, Epilachna
varivestis (Coccinellidae)
*1,
, *2
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Athula B. Attygalle, *, Shang-Cheng Xu1,
Kevin D. McCormick and Jerrold Meinwald
Curtis L. Blankespoor and Thomas Eisner
Baker Laboratory, Department of Chemistry, Cornell University, Ithaca, New
York 14853 U.S.A.
Section of Neurobiology and Behavior, Cornell University, Ithaca, New York
14853 U.S.A.
Received 12 March 1993;
accepted 30 March 1993.
Available online 12 March 2001.
Abstract
Two novel alkaloids, 2-(12-aminotridecyl)-pyrrolidine and its
1-(2-hydroxyethyl) derivative, are characterized from extracts of adult Mexican
bean beetles. These pyrrolidines, together with a previously identified
homotropane alkaloid, euphococcinine, account for 90% of the alkaloids present
in this beetle. A number of piperidine derivatives are also identified as minor
components. The total mixture represents the most complex bouquet of alkaloids
reported hitherto from any coccinellid beetle.
Graphical Abstract
Several new alkaloids, including 2-(12-aminotridecyl)-pyrrolidine
(G) and its l-(2- hydroxyethyl) derivative
(I), are characterized from extracts of adult Mexican bean
beetles.
Article Outline
- • References
*1
This publication is dedicated to Prof. Carl Djerassi on the ocassion of his
seventieth birthday.
*2
Paper no. 119 in the series “Defense Mechanisms of Arthropods.”
1
Permanent address: Jiangsu Pesticide Research Institute, Nanjing 210036,
People's Republic of China.